![]() They consist of recession of the hairline, hirsutism, small breasts, and generalized muscular overdevelopment, with deepening of the voice. To a variable extent, there are features of adrenal androgen excess in women with Cushing's syndrome these are absent in the case of adenoma, most severe with carcinoma, and present to an intermediate degree with Cushing's disease. In 80% of cases, postprandial hyperglycemia is present, and in 20%, there is an elevated fasting plasma glucose level. Osteoporosis (common), with back pain from compression fractures of the lumbar vertebrae as well as rib fractures. Proximal myopathy with marked weakness, especially in the quadriceps femoris, making unaided rising from a chair difficult.Įmotional lability, irritability, difficulty in sleeping, and sometimes psychotic personality. Striae (red and depressed) over the abdomen and thighs. ![]() Obesity (with sparing of the extremities), moon face, and fat pads of the supraclavicular and dorsocervical areas (buffalo hump). ![]()
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